Etodolac tab 400 mg


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Common Use

Etodolac is a non-steroidal anti-inflammatory drug used to relieve pain, swelling, and joint stiffness due to various conditions. Etodolac tab 400 mg blocks the release of natural hormones that are responsible for pain and inflammation. Its common brand names include Lodine and Lodine XL.

Dosage And Direction of Etodolac tab 400 mg

Before taking the Etodolac medication, one should read the Medication Guide provided by the pharmacist and also consult a doctor for any questions. The most common initial dose for various conditions is the Etodolac 200 mg which can then be adjusted to Etodolac 300 mg, Etodolac tab 400 mg, or Etodolac 500 mg tablets. The drug is taken orally, 2 to 3 times a day as directed by the doctor. The dosage varies according to the severity of the condition, and the patient’s age, and the reaction to the drug, and should only be adjusted after close monitoring by the doctor. The drug may increase the maximum dose to 1000 mg or 1200 mg a day if necessary.


Etodolac should be used with cautions with the following conditions:
· Hepatic disease due to an increased risk of developing complications. When the patient manifests jaundice, the treatment should be discontinued.
· Patients with diabetes, oedema, heart disease, dehydration, renal disease or failure, rheumatoid arthritis, sepsis, systematic lupus erythematosus, dental disease, and renal impairment should take the drug under close observation.
· Drug use may intensify hypertension and congestive heart failure. This can, in turn, increase the risks of severe and fatal cardiovascular thromboembolism, myocardial infarction, and stroke.
· Patients undergoing surgery requires high degree of homeostasis.
· Drug use in children, pregnant, and breastfeeding women should be monitored closely by the doctor.


· Etodolac is contraindicated in patients with a known hypersensitivity to NSAID drugs, patients with a history of or active GI disease such as peptic ulcer disease, ulcerative colitis, and GI perforation or GI bleeding

Possible Side Effects

Apart from its needed benefits, Etodolac 500 mg tab may manifest the following symptoms:
· Nausea
· Diarrhea
· Dizziness or drowsiness
· Stomach upset
· Easy bruising or bleeding
· Painful swallowing
· Mood changes
· Change in the urine amount
· Vision changes
· Sudden weight gain
· Swelling ankles or feet
· Fatigue
· Rash
· itching
· Swelling of the face/tongue/throat
· Trouble breathing
· Severe dizziness

Drug Interaction

Etodolac tab 400 mg if interacted with other medications like antiplatelet drugs may then it may increase the risk of bleeding. This includes clopidogrel blood thinners, among others. One should inform the doctor of all prescription and non-prescription medications containing pain or fever relievers such as aspirin and NSAIDs. Etodolac tablet 400 mg also affects some laboratory tests, thereby causing unsatisfactory test results.

Missed Dose

A missed dose should be taken immediately or skipped when it is time for the next scheduled dose. Taking more than the recommended dose should not be practised, and one should take Etodolac at regular times so as not to miss a dose.


If one takes more Etodolac 400 mg cap than recommended, they should contact their health care provider immediately for medical assistance. Symptoms may include trouble breathing and fainting.


The patient should take care not to store the drug close to light, excessive heat of above 104 degrees F, and moisture. Etodolac tab 400 mg should be kept at controlled room temperatures of between 68 and 77 degrees F, in its original package until time of use, and away from children and pets. Care should be taken not to flush medications down the toilet or pour them into a drain. If no longer needed, the unused or expired drugs should be disposed of as directed by the doctor.


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Strength (mg)

200, 300